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Recent Publications by Organon Laboratories Ltd.: |  | |
| Structure-activity relationships and CoMFA of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic properties.
The N-3 position of a series of 3-phenoxypropyl piperidine... | Department of Chemistry, Organon Laboratories Ltd, Newhouse, Lanarkshire | Bioorg Med Chem. 2008 Mar 15;16(6):2829-51. Epub 2008 Jan 10.
DOI Direct Link |
| Innovative approaches for the treatment of depression: targeting the HPA axis.
Altered activity of the hypothalamic pituitary adrenal (HPA) axis is one... | Department of Molecular Pharmacology, Organon Laboratories Ltd, Newhouse, | Neurochem Res. 2008 Apr;33(4):691-707. Epub 2007 Oct 25.
DOI Direct Link |
| Design, structure activity relationships and X-Ray co-crystallography of non-steroidal LXR agonists.
The Liver X Receptor (LXR) alpha and beta isoforms are members of the type... | Department of Chemistry, Organon Laboratories Ltd., Newhouse, Motherwell, | Curr Med Chem. 2008;15(2):195-209. |
| The potential influence of CO2, as an agent for euthanasia, on the pharmacokinetics of basic compounds in rodents.
Rodent tissue distribution and pharmacokinetic studies were performed on... | Department of Pharmacology, Organon Laboratories Ltd., Newhouse, | Drug Metab Dispos. 2008 Feb;36(2):375-9. Epub 2007 Nov 15.
DOI Direct Link |
| Non-steroidal LXR agonists; an emerging therapeutic strategy for the treatment of atherosclerosis.
The Liver X Receptor (LXR) alpha and beta isoforms are members of the type... | Department of Chemistry, Organon Laboratories Ltd., Newhouse ML1 5SH, | Recent Pat Cardiovasc Drug Discov. 2006 Jan;1(1):21-46. |