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Recent Publications by Pfizer Global Research and Development: |  | |
| In vitro assays for cyclooxygenase activity and inhibitor characterization.
Cyclooxygenases (COX), or Prostaglandin H Synthases (PGHS), are the target... | Pfizer Global Research and Development, Chesterfield, MO, USA. | Methods Mol Biol. 2010;644:131-44.
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| Techniques used to characterize the binding of cyclooxygenase inhibitors to the cyclooxygenase active site.
Inhibitors of enzyme-catalyzed reactions are typically characterized by... | Pfizer Global Research and Development, Chesterfield, MO, USA. | Methods Mol Biol. 2010;644:121-9.
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| Purification of recombinant human COX-1 and COX-2.
Human recombinant COX-1 and COX-2 was prepared in a purified form. The... | Pfizer Global Research and Development, Inflammation Research, | Methods Mol Biol. 2010;644:21-9.
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| Strategies for discovering and derisking covalent, irreversible enzyme inhibitors.
This article presents several covalent inhibitors, including examples of... | Pfizer Global Research and Development, Groton, CT 06340, USA. | Future Med Chem. 2010 Jun 1;2(6):949-964. |
| 1-Methyl-1H-pyrrole-2-carbonitrile containing tetrahydronaphthalene derivatives as non-steroidal progesterone receptor antagonists.
Non-steroidal 1-methyl-1H-pyrrole-2-carbonitrile containing... | Chemical Sciences, Pfizer Global Research and Development, 500 Arcola | Bioorg Med Chem Lett. 2010 Jun 25.
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