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Recent Publications by GlaxoSmithKline Medicine Research Centre: |  | |
| Functional role of Calcium-stimulated adenylyl cyclase 8 in adaptations to psychological stressors in the mouse: implications for mood disorders.
The Ca(2+)/calmodulin stimulated adenylyl cylcase 8 (AC8) is a pure Ca(2+)... | Neurosciences CEDD, GlaxoSmithKline Medicine Research Centre, via Fleming | Neuroscience. 2010 Jul 15.
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| 1-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes: a new series of potent and selective triple reuptake inhibitors.
The discovery of new highly potent and selective triple reuptake... | Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline | J Med Chem. 2010 Mar 25;53(6):2534-51.
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| Alterations of behavioral and endocrinological reactivity induced by 3 brief social defeats in rats: relevance to human psychopathology.
In the realm of animal models of psychopathology, social stress based... | Neurosciences CEDD, GlaxoSmithKline Medicine Research Centre, 37135 | Psychoneuroendocrinology. 2009 Oct;34(9):1405-16. Epub 2009 May 30.
DOI Direct Link |
| Anxiolytic-like effect of the selective neuropeptide Y Y2 receptor antagonist BIIE0246 in the elevated plus-maze.
The involvement of Neuropeptide Y (NPY) in the pathophysiology of mood... | Department of Biology, Psychiatry CEDD, GlaxoSmithKline Medicine Research | Peptides. 2006 Dec;27(12):3202-7. Epub 2006 Sep 7.
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| 1,2,4-triazol-3-yl-thiopropyl-tetrahydrobenzazepines: a series of potent and selective dopamine D(3) receptor antagonists.
The discovery of new highly potent and selective dopamine D3 receptor... | Psychiatry Centre of Excellence, Molecular Discovery Research, and Safety | J Med Chem. 2007 Oct 18;50(21):5076-89. Epub 2007 Sep 15.
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