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Recent Publications by Biotica: |  | |
| Glycosylation engineering of spinosyn analogues containing an L-olivose moiety.
Biosynthetic genes encoding proteins involved in the first steps of... | Biotica Technology Ltd, Chesterford Research Park, Cambridge, UK CB10 1XL. | Org Biomol Chem. 2009 Apr 21;7(8):1705-8. Epub 2009 Mar 12.
DOI Direct Link |
| Chapter 14. Biosynthesis of nonribosomal peptide precursors.
Nonribosomal peptides are natural products typically of bacterial and... | Biotica, Chesterford Research Park, Little Chesterford, Essex, United | Methods Enzymol. 2009;458:353-78.
DOI Direct Link |
| Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties.
The glycosylation of natural product scaffolds with highly modified... | Biotica Technology Ltd, Chesterford Research Park, Little Chesterford, | Org Biomol Chem. 2008 Sep 21;6(18):3315-27. Epub 2008 Jul 28.
DOI Direct Link |
| Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.
A biosynthetic medicinal chemistry approach was applied to the... | Biotica Technology Limited, Chesterford Research Park, Nr. Saffron Walden, | J Med Chem. 2008 Sep 25;51(18):5494-7.
DOI Direct Link |
| Molecular characterization of macbecin as an Hsp90 inhibitor.
Macbecin compares favorably to geldanamycin as an Hsp90 inhibitor, being... | Biotica Technology Limited, Chesterford Research Park, Essex CB10 1XL, | J Med Chem. 2008 May 8;51(9):2853-7. Epub 2008 Mar 22.
DOI Direct Link |
