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Human Genome Sciences

Recent Publications on human genome sciences :

B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.
Peripheral B-cell numbers are tightly regulated by homeostatic mechanisms...
Department of Immunology, Box 3010, Duke University Medical Center, Int Immunol. 2010 Aug;22(8):681-91. Epub 2010 May 31.
DOI Direct Link
Belimumab: Anti-BLyS Monoclonal Antibody; Benlysta; BmAb; LymphoStat-B.
Belimumab is a fully human monoclonal antibody for the treatment of...
Drugs R D. 2010;10(1):55-65. doi: 10.2165/11538300-000000000-00000.
DOI Direct Link
28th Annual JPMorgan Healthcare Conference--Human Genome Sciences and Celgene.
The JPMorgan Healthcare Conference, held in San Francisco, included...
Thomson Reuters, 77 Hatton Garden, London, EC1N 8JS, UK. IDrugs. 2010 Mar;13(3):135-8.
Human Genome Sciences trial data wow lupus community.
IMPORTANCE OF THE FIELD: Agents that activate the TNF-related...
Nat Biotechnol. 2009 Sep;27(9):779-80.
DOI Direct Link
Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) Receptor-1 and Receptor-2 agonists for cancer therapy.
IMPORTANCE OF THE FIELD: Agents that activate the TNF-related...
Human Genome Sciences, Rockville, MD 20850, USA. Expert Opin Biol Ther. 2010 Jan;10(1):1-18.
DOI Direct Link

Patents:

US Patent No.Title
7579001 Antagonists of TWEAK and of TWEAK receptor and their use to treat immunological disorders
7605236 Antibodies that immunospecifically bind to B lymphocyte stimulator protein
7608600 Modified 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections
7611846 Diagnostic methods involving human growth factor huXAG-1
7612181 Dual variable domain immunoglobulin and uses thereof