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Recent Publications on genomics novartis : | ||
| Simple sequence repeats and genome plasticity in Streptococcus agalactiae.
Simple sequence repeats (SSRs) and their role in phase variation have been... | Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy. | J Bacteriol. 2010 Aug;192(15):3990-4000. Epub 2010 May 21.
DOI Direct Link |
| Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
ALK (anaplastic lymphoma kinase) is an RTK (receptor tyrosine kinase) of... | The Genomics Institute of the Novartis Research Foundation, San Diego, CA | Biochem J. 2010 Aug 27;430(3):425-37.
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| Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1.
A novel series of benzoazepin-2-ones were designed and synthesized... | Genomics Institute of the Novartis Research Foundation, San Diego, CA | Bioorg Med Chem Lett. 2010 Jul 1;20(13):3897-902. Epub 2010 May 12.
DOI Direct Link |
| Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus.
Streptococcus pneumoniae, like many other Gram-positive bacteria,... | Genomics Institute of the Novartis Research Foundation, San Diego, | PLoS One. 2010 Jun 15;5(6):e10919.
DOI Direct Link |
| Genome-based approaches to vaccine development.
The hundreds of bacterial genome sequences available together with... | Novartis Vaccines, Via Fiorentina 1, 53100 Siena, Italy. | J Mol Med. 2010 Feb;88(2):143-7.
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