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Genomics Novartis

Recent Publications on genomics novartis :

Simple sequence repeats and genome plasticity in Streptococcus agalactiae.
Simple sequence repeats (SSRs) and their role in phase variation have been...
Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy. J Bacteriol. 2010 Aug;192(15):3990-4000. Epub 2010 May 21.
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Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
ALK (anaplastic lymphoma kinase) is an RTK (receptor tyrosine kinase) of...
The Genomics Institute of the Novartis Research Foundation, San Diego, CA Biochem J. 2010 Aug 27;430(3):425-37.
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Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1.
A novel series of benzoazepin-2-ones were designed and synthesized...
Genomics Institute of the Novartis Research Foundation, San Diego, CA Bioorg Med Chem Lett. 2010 Jul 1;20(13):3897-902. Epub 2010 May 12.
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Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus.
Streptococcus pneumoniae, like many other Gram-positive bacteria,...
Genomics Institute of the Novartis Research Foundation, San Diego, PLoS One. 2010 Jun 15;5(6):e10919.
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Genome-based approaches to vaccine development.
The hundreds of bacterial genome sequences available together with...
Novartis Vaccines, Via Fiorentina 1, 53100 Siena, Italy. J Mol Med. 2010 Feb;88(2):143-7.
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